New Way to Combat Muscle Loss Due to Type 1 Diabetes
Those suffering from Type 1 diabetes know first-hand the effects the disease has on skeletal muscle. Studies have shown that due to the loss of muscle stem cells from the early stages of the disease, that down the road almost all those suffering will eventually find themselves losing some muscle. Researchers wanted to figure out if there is a way to stop or prevent this from happening. The following study shows what took place and how they plan on sparing muscle loss.
Put up a fight against Type 1 diabetes
Being that there is no cure for Type 1 diabetes, McMaster University researchers were trying to better understand what happens inside the body that causes the deterioration of skeletal muscle. This autoimmune disease generally is found in individuals who are in the early years of childhood and adolescence. In order to treat the disease, the individual will need to give themselves insulin injections throughout the rest of their life in order to manage their blood glucose levels. Usually, a parent or guardian needs to give the child injections until they are responsible enough or know how and are able to inject themselves with insulin without potentially doing harm to their body.
One researcher stated that “through research with both mice and humans, we’ve shown that Type 1 diabetes negatively impacts muscle, and by improving muscle health we can reduce blood sugar levels and improve the response to insulin.” The team of researchers noticed that in order to preserve muscle, they would need to reduce the hormone myostatin which is naturally secreted by the body. Reduce myostatin, reduce muscle loss. Interestingly enough, through their research, they noticed that by reducing myostatin, the muscle was much more sensitive to insulin and better able to deal with glucose even without insulin being injected and additionally showed an overall decrease in blood sugar levels.
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